COMT Protein (AA 51-271)

N° du produit ABIN666744

Cette protéine Recombinant COMT est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour COMT Protein (AA 51-271) (ABIN666744)

Antigène: COMT (Catechol-O-Methyltransferase (COMT))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: > 95 % by SDS - PAGE

Détail du produit

Attributs du protein: AA 51-271

Attributs du produit: COMT, 51-271 aa, Human, Recombinant, E.coli

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM MgCl2, 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: COMT (Catechol-O-Methyltransferase (COMT))

Autre désignation: COMT

Sujet: Catechol-O-methyltrasferase (COMT) is an enzyme that catalyses the transfer of the methyl group of S-adenosylmethionine (SAM) into catechol substrates such as levodopa, dopamine, epinephrine, and norepinephirine in the presence of Mg2+. COMT appears to be located in the postsynaptic neuron and plays roles in the metabolism of catechol estrogens and the inactivation of catecholamine neurotransmitters though enzymatic degradation. COMT inhibitors prevent levodopa degradation, increase its availability and are used in the treatment of patients with Parkinson's disease. Recombinant human COMT protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Catechol-O-methyltransferase , Catechol-O-methyltransferase , COMT. NCBI no.: NP_000745

Poids moléculaire: 24.4 kDa (221 aa), confirmed by MALDI-TOF.

Pathways: Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome