Cyclin H Protein (CCNH) (GST tag)

N° du produit ABIN6699745

N° du produit (Fournisseur): 009-001-r80s

Cette protéine Recombinant Cyclin H est produite dans Insect cells (Sf9).

Aperçu rapide pour Cyclin H Protein (CCNH) (GST tag) (ABIN6699745)

Antigène: Cyclin H (CCNH)

Type de proteíne: Recombinant

Origine: Humain

Source: Insect cells (Sf9)

Application: Western Blotting (WB)

Pureté: >90%

Détail du produit

Purification/Conjugué: Cette Cyclin H protéine est marqué à la GST tag.

N° du produit (Fournisseur): 009-001-r80s

Fournisseur: Rockland

Fonction: CyclinH recombinant protein-GST fusion protein

Purification: Recombinant full length human CyclinH was expressed in insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >90% by densitometry.

Information d'application

Indications d'application:

Application Note: CyclinH Protein is stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol. CyclinH Protein is suitable for use in Western Blot. Expect a band approximately ~ 39 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

Western Blot Dilution: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 μg/μL

Buffer: CyclinH Protein is stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol.

Stock: -80 °C

Stockage commentaire: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Cyclin H (CCNH)

Autre désignation: CCNH

Sujet:

Synonyms: CCNH, CAK, p34, p37, Cyclin-H, MO15-associated protein

Background: Cyclin H is related to the highly conserved cyclin family. Cyclin family members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Cyclin H forms a complex with CDK7 kinase and the ring finger protein MAT1 which is able to phosphorylate CDK2 and CDC2 kinases and thus act as a CDK-activating kinase (CAK) (1). Cdk-activating kinase complex is a component of human transcription factor TFIIH and plays an important role in the processes of transcription, DNA repair, and cell cycle progression (2). Cyclin H Protein is ideal for investigators involved in Signaling Proteins, Cell Cycle Proteins, Cancer, and Cell Cycle research.

NCBI Accession: NM_001239

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase