FLT3LG Protéine
Aperçu rapide pour FLT3LG Protéine (ABIN6699868)
Antigène
Voir toutes FLT3LG ProtéinesType de proteíne
Origine
Source
Application
Pureté
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N° du produit (Fournisseur)
- 009-001-u86-0100
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Fournisseur
- Rockland
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Fonction
- Human Flt-3 Ligand Recombinant Protein
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Purification
- Flt-3 Ligand purity was determined to be greater than 98% as determined by analysis by HpLC, UV-Spectroscopy at 280nm and by reducing and non-reducing SDS-pAGE.
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niveau d'endotoxine
- Measured by LAL is typically ≤ 1 EU/μg protein.
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Biological Activity Comment
- The activity is determined by the dose-dependent production of OCI-AML5 cell proliferation and is typically 10 ng/mL.
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Indications d'application
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Application Note: Flt-3 Ligand Recombinant Protein has been tested by SDS-PAGE and biological activity and is suitable as a control for polyclonal or monoclonal anti- Flt-3 Ligand in immunological assays. Buffer Formulation: 10 mM sodium phosphate and 50 mM sodium chloride, pH 7.5.
Other: User Optimized
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 100 μL
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Buffer
- Buffer Formulation: 10 mM sodium phosphate and 50 mM sodium chloride, pH 7.5.
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Agent conservateur
- Without preservative
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
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Date de péremption
- 6 months
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- FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))
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Autre désignation
- FLT3LG
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Sujet
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Synonyms: FLt3 L, Fms-related tyrosine kinase 3 ligand
Background: FMS-related Tyrosine Kinase 3 Ligand (FLT-3 Ligand) is a growth factor important for the proliferation of hematopoietic cells. FLT-3 Ligand binds to, and transmits signals through, the receptor tyrosine kinase known as FMS-like Tyrosine Kinase-3 (FLT-3). FLT-3 Ligand promotes long-term expansion and differentiation of human pro-B cells in the presence of IL-7 or in combination of IL-7 and IL-3. Human FLT-3 Ligand can stimulate the proliferation of cells expressing murine FLT-3 receptors. Recombinant human FLT-3 Ligand is a non-glycosylated protein, containing 155 amino acids, with a molecular weight of 17.7 kDa.
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UniProt
- P49771
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Pathways
- Signalisation RTK
Antigène
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