IL-15 Protéine

N° du produit ABIN6700033

N° du produit (Fournisseur): 009-001-v53-0100

Cette protéine Recombinant IL-15 est produite dans Escherichia coli (E. coli).

Aperçu rapide pour IL-15 Protéine (ABIN6700033)

Antigène: IL-15 (IL15) (Interleukin 15 (IL15))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: 98,00%

Détail du produit

N° du produit (Fournisseur): 009-001-v53-0100

Fournisseur: Rockland

Fonction: Human Interleukin-15 Recombinant Protein

Purification: Interleukin-15 purity was determined to be greater than 98% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.

niveau d'endotoxine: Measured by LAL is typically ≤ 1 EU/μg protein.

Biological Activity Comment: The activity is determined by the dose-dependant stimulation of the proliferation of mouse CTLL-2 cells and is typcially less than 0.5 ng/mL.

Information d'application

Indications d'application:

Application Note: Interleukin-15 Recombinant Protein has been tested by biological activity and is suitable as a control for polyclonal or monoclonal anti-Interleukin-15 in immunological assays. Lyophilized in 10 mM sodium bicarbonate, pH 8.5.

Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 100 μL

Buffer: Lyophilized in 10 mM sodium bicarbonate, pH 8.5.

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Date de péremption: 6 months

Détail du antigène

Antigène: IL-15 (IL15) (Interleukin 15 (IL15))

Autre désignation: IL15

Sujet:

Synonyms: IL-T

Background: Interleukin 15 (IL-15) is a widely expressed pro-inflammatory cytokine related to IL-2. IL-15 promotes activation of T cells, neutrophils and macrophages and is critical to dendritic cell function in several model systems. IL-15 has been shown to play a role in several inflammatory disorders, including rheumatoid arthritis, psoriasis and pulmonary inflammatory diseases. Emerging data suggests that IL-15 may serve as a good therapeutic target, as there appears to be a beneficial effect of IL-15 neutralization in models of psoriasis and diabetes. Human IL-15 shows activity on mouse cells. Recombinant human IL-15 is a non-glycosylated protein, containing 114 amino acids, with a molecular weight of 12.8 kDa.

UniProt: P40933

Pathways: Signalistation JAK/STAT, Glycosaminoglycan Metabolic Process