Neurotrophin 4 Protein (NTF4)

N° du produit ABIN6700310

N° du produit (Fournisseur): 009-001-w07-0010

Cette protéine Recombinant Neurotrophin 4 est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour Neurotrophin 4 Protein (NTF4) (ABIN6700310)

Antigène: Neurotrophin 4 (NTF4)

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: 97,00%

Détail du produit

N° du produit (Fournisseur): 009-001-w07-0010

Fournisseur: Rockland

Fonction: Human Neurotrophin-4 Recombinant Protein

Purification: Neurotrophin-4 purity was determined to be greater than 97% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.

niveau d'endotoxine: Measured by LAL is typically ≤ 1 EU/μg protein.

Biological Activity Comment: Proliferation of a neuroblastoma cell line stably expressing TrkB (BR6) ED50 ≤ 20 ng/mL (≥ 5.0 x 10^4 units/mg).

Information d'application

Indications d'application:

Application Note: Neurotrophin-4 Recombinant Protein is suitable as a control for polyclonal or monoclonal anti-Neurotrophin-4 in immunological assays.

Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 10 μL (10-100 μL)

Concentration: 0.1 mg/mL

Buffer:

Buffer: 0.1 % Trifluoroacetic acid

Stabilizer: None

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Date de péremption: 6 months

Détail du antigène

Antigène: Neurotrophin 4 (NTF4)

Autre désignation: NTF4

Sujet:

Synonyms: Neurotrophin 5 (NT-5), Neurotrophic Factor 4

Background: Neurotrophin-4 (NT-4) is an important member of the nerve growth factor (NGF) family of proteins along with NT-3, BDNF and NGF. Neurotrophins act in a paracrine and/or autocine manner to control neuronal numbers and dendrite outgrowth. These functions are thought to be communicated by TrkB, a receptor tryrosine kinase that NT-4 shares with BDNF. Recombinant human NT-4 is a non-glycosylated, non-covalently linked homodimer, containing two 131 amino acid chains, with a total molecular weight of 28.1 kDa.

UniProt: P34130

Pathways: Signalisation RTK