Stathmin 1 Protein (STMN1) (His tag)

N° du produit ABIN6700567

N° du produit (Fournisseur): 009-001-t58s

Cette protéine Recombinant Stathmin 1 est produite dans Escherichia coli (E. coli).

Aperçu rapide pour Stathmin 1 Protein (STMN1) (His tag) (ABIN6700567)

Antigène: Stathmin 1 (STMN1)

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: Western Blotting (WB)

Pureté: >90%

Détail du produit

Purification/Conjugué: Cette Stathmin 1 protéine est marqué à la His tag.

N° du produit (Fournisseur): 009-001-t58s

Fournisseur: Rockland

Fonction: Stathmin recombinant protein-HIS Epitope

Purification: Recombinant full-length human Stathmin protein was expressed in E. coli cells using an N-Terminal his epitope. The purity was determined to be >90% by densitometry.

Information d'application

Indications d'application:

Application Note: Stathmin Protein is stored in 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25 % glycerol. Stathmin Protein is suitable for use in Western Blot. Expect a band approximately ~19 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

Western Blot Dilution: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 μg/μL

Buffer: Stathmin Protein is stored in 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25 % glycerol.

Stock: -80 °C

Stockage commentaire: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Stathmin 1 (STMN1)

Autre désignation: STMN1

Sujet:

Synonyms: STMN1, C1orf215, FLJ32206, Lag, LAP18, MGC138869, MGC138870, OP18, PP17, PP19, PR22, SMN, Stathmin

Background: Stathmin is a ubiquitous, highly conserved protein present in the cytoplasm in a variety of unphosphorylated and phosphorylated forms. Stathmin functions as an intracellular relay integrating regulatory signals of the cellular environment (1). Stathmin is involved in the regulation of the microtubule filament system. Stathmin binds tubulin in a ternary complex, with 2 tubulins for every stathmin and this complex interferes with microtubule dynamics in vitro and in vivo. Overexpression of several stathmin mutants suggest that stathmin induces depolymerization of interphase and mitotic microtubules in its unphosphorylated state, but is inactivated by phosphorylation in mitosis (2). Stathmin Protein is ideal for investigators involved in Signaling Proteins, Microtubule/Actin Associated Proteins, Cancer, Invasion/Metastasis, and Neurobiology research.

Pathways: Signalisation MAPK, Dynamique des Microtubules