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C5A Protein (AA 678-751)

C5a Origine: Cynomolgus Hôte: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE. Active
N° du produit ABIN6809880
  • Antigène Voir toutes C5A (C5a) Protéines
    C5A (C5a) (Complement Component 5a (C5a))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    AA 678-751
    Origine
    • 6
    • 4
    • 4
    • 2
    • 1
    Cynomolgus
    Source
    • 15
    • 1
    Escherichia coli (E. coli)
    Pureté
    >95 % as determined by SDS-PAGE.
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product C5a Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Stock
    -20 °C
  • Antigène
    C5A (C5a) (Complement Component 5a (C5a))
    Autre désignation
    Complement Component C5a (C5a Produits)
    Synonymes
    C5a Protein, C5b Protein, CPAMD4 Protein, Hc Protein, RGD1561905 Protein, complement C5 Protein, C5 Protein
    Sujet
    Complement Component C5a (C5a) is also known as C5,and is a protein fragment released from complement component C5.,is a potent chemotactic factor for human peripheral blood neutrophils and monocytes, and is believed to play an important role in a number of inflammatory conditions. There are several functions in the below: C5a is an anaphylatoxin, causing the release of histamine from mast cells, C5a is effective leukocyte chemoattractants, causing the accumulation of white blood cells, especially neutrophil granulocytes, at sites of complement activation, C5a activates white blood cells by increasing avidity for white blood cell integrins and upregulating the Lipoxygenase pathway for arachidonic acid metabolism, C5a is a powerful inflammatory mediator, and seems to be a key factor in the development of pathology of many inflammatory diseases involving the complement system, C5a modulates balance between activating versus inhibitory IgG Fc receptors on leukocytes, thereby enhancing autoimmune response.
    Poids moléculaire
    8.4 kDa
    NCBI Accession
    XP_015292262
    Pathways
    Système du Complément, Carbohydrate Homeostasis
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