CCL3 Protein (AA 24-92)
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- Antigène Voir toutes CCL3 Protéines
- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 24-92
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Application
- Cell Migration Assay (CMA)
- Séquence
- SLAADTPTAC CFSYTSRQIP QNFIADYFET SSQCSKPGVI FLTKRSRQVC ADPSEEWVQK YVSDLELSA
- Attributs du produit
- Recombinant Human CCL3 (MIP-1alpha)
- Pureté
- > 97 % by SDS PAGE
- niveau d'endotoxine
- <0.01 EU per 1μg of the protein by the LAL method
- Biological Activity Comment
- EC50 = 0.2 nM determined by Migration Assay in cells expressing recombinant CCR5
- Top Product
- Discover our top product CCL3 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
- Stock
- -20 °C,-80 °C
- Stockage commentaire
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. - Date de péremption
- 12 months
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- Antigène
- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
- Autre désignation
- CCL3 (MIP-1alpha) (CCL3 Produits)
- Synonymes
- MIP-1alpha Protein, G0S19-1 Protein, LD78ALPHA Protein, MIP-1-alpha Protein, MIP1A Protein, SCYA3 Protein, MIP-1a Protein, Scya3 Protein, AI323804 Protein, LD78alpha Protein, MIP1-(a) Protein, MIP1-alpha Protein, Mip1a Protein, CCL3L1 Protein, CCL3L3 Protein, chemokine (C-C motif) ligand 3 Protein, C-C motif chemokine ligand 3 Protein, CCL3 Protein, Ccl3 Protein
- Sujet
- Macrophage inflammatory proteins 1-alpha (MIP1alpha)(CCL3) binds to cell surface receptors CCR1 and CCR5. It is proinflammatory, leading to chemotaxis and activation of immune cells. It also inhibits proliferation of hematopoietic stem cells. Moreover, by binding to one of the HIV coreceptors, CCR5, it suppresses HIV infection.
- Poids moléculaire
- 7.716 kDa
- UniProt
- P10147
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Autophagy
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