CCL3 Protein (AA 24-92) (His tag)

N° du produit ABIN666794

Détail du produit

Antigène: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Type de proteíne: Recombinant

Attributs du protein: AA 24-92

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CCL3 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: CCL3, 24-92aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 10mM Sodium Citrate ( pH3.5) containing 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Autre désignation: CCL3 (CCL3 Produits)

Synonymes: MIP-1alpha Protein, G0S19-1 Protein, LD78ALPHA Protein, MIP-1-alpha Protein, MIP1A Protein, SCYA3 Protein, MIP-1a Protein, Scya3 Protein, AI323804 Protein, LD78alpha Protein, MIP1-(a) Protein, MIP1-alpha Protein, Mip1a Protein, CCL3L1 Protein, CCL3L3 Protein, chemokine (C-C motif) ligand 3 Protein, C-C motif chemokine ligand 3 Protein, CCL3 Protein, Ccl3 Protein

Sujet: CCL3, also known as, macrophage inflammatory protein-1alpha (MIP-1alpha), is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes. This protein has been identified as one of the major HIV-SFs produced by CD8+ T cells, along with MIP-1beta and RANTES. It acts as an inhibitor of different strains of HIV-1, HIV-2 and SIV infection in a dose-dependent manner. Recombinant human CCL3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: C-C motif chemokine 3, G0S19-1, LD78ALPHA. MIP-1-alpha. MIP1A. SCYA3. NCBI no.: NP_002974

Poids moléculaire: 10.0 kDa (90aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Pathways: Cellular Response to Molecule of Bacterial Origin, Autophagy