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CCL5 Protein (AA 24-91) (Biotin)

CCL5 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
N° du produit ABIN6952202
  • Antigène Voir toutes CCL5 Protéines
    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    AA 24-91
    Origine
    • 22
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Source
    • 32
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette CCL5 protéine est marqué à la Biotin.
    Application
    Cell Migration Assay (CMA)
    Séquence
    SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
    Attributs du produit
    Biotininylated Recombinant Human CCL5 (Rantes)
    Pureté
    > 97 % by SDS PAGE
    niveau d'endotoxine
    <0.01 EU per 1μg of the protein by the LAL method
    Biological Activity Comment
    EC50 = 0.25-0.50 nM determined by Migration Assay of recombinant CCR5 containing cells
    Top Product
    Discover our top product CCL5 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.
    Date de péremption
    12 months
  • Antigène
    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
    Autre désignation
    CCL5 (Rantes) (CCL5 Produits)
    Synonymes
    Rantes Protein, Scya5 Protein, D17S136E Protein, RANTES Protein, SCYA5 Protein, SIS-delta Protein, SISd Protein, TCP228 Protein, eoCP Protein, MuRantes Protein, C-C motif chemokine 5-like Protein, C-C motif chemokine ligand 5 Protein, chemokine (C-C motif) ligand 5 Protein, LOC100230935 Protein, CCL5 Protein, Ccl5 Protein
    Sujet
    Regulated on Activation, Normal T cell Expressed and Secreted (RANTES) (CCL5) is a proinflammatory chemokine that induces migration and activation of leukocytes, as well as implication in HIV infection. It binds to cell surface receptors CCR1, CCR3, CCR4, and CCR5. Its biological effects on leukocyte activation and HIV infection displays dependence on concentration and on the binding of cell surface glycosaminoglycans.
    Poids moléculaire
    10.270 kDa
    UniProt
    P13501
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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