GDF15 Protein (AA 197-308) (His tag)
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- Antigène Voir toutes GDF15 Protéines
- GDF15 (Growth Differentiation Factor 15 (GDF15))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 197-308
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette GDF15 protéine est marqué à la His tag.
- Séquence
- AA 197-308
- Pureté
- >90 % as determined by reduced SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product GDF15 Protéine
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Growth Differentiation Factor 15 (GDF15) (AA 197-308) protein (His tag)
GDF15 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Growth Differentiation Factor 15 (GDF15) (AA 197-308) protein (Fc Tag)GDF15 Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Differentiation Factor 15 (GDF15) (AA 189-303) protein (Fc Tag)GDF15 Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Differentiation Factor 15 (GDF15) (AA 197-308) protein (Fc Tag,Biotin)GDF15 Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Differentiation Factor 15 (GDF15) (AA 189-303) protein (His tag)GDF15 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Growth Differentiation Factor 15 (GDF15) (AA 197-308) protein (Fc Tag)GDF15 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 92 % as determined by HPLC
Growth Differentiation Factor 15 (GDF15) (AA 193-308) protein (His tag)GDF15 Origine: Cynomolgus Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Growth Differentiation Factor 15 (GDF15) (AA 197-307) protein (His tag)GDF15 Origine: Chien Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Growth Differentiation Factor 15 (GDF15) (AA 189-303) protein (Fc Tag,Biotin)GDF15 Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Differentiation Factor 15 (GDF15) (AA 197-308) protein (Fc Tag,Biotin)GDF15 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 60 % ACN, 0.085 % TFA
- Conseil sur la manipulation
- Please avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
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- Antigène
- GDF15 (Growth Differentiation Factor 15 (GDF15))
- Autre désignation
- GDF-15 (GDF15 Produits)
- Synonymes
- GDF15 Protein, GDF-15 Protein, MIC-1 Protein, MIC1 Protein, NAG-1 Protein, PDF Protein, PLAB Protein, PTGFB Protein, SBF Protein, growth differentiation factor 15 Protein, GDF15 Protein, Gdf15 Protein
- Sujet
- Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1). Expression of MIC-1 mRNA in monocytoid cells is up-regulated by a variety of stimuli associated with activation, including interleukin 1β, tumor necrosis factor α (TNF-α), interleukin 2, and macrophage colony-stimulating factor but not interferon γ, or lipopolysaccharide (LPS). It is highly expressed in cardiomyocytes, adipocytes, macrophages, endothelial cells, and vascular smooth muscle cells in normal and pathological condition. GDF-15 increases during tissue injury and inflammatory states and is associated with cardiometabolic risk. Increased GDF-15 levels are associated with cardiovascular diseases such as hypertrophy, heart failure, atherosclerosis, endothelial dysfunction, obesity, insulin resistance, diabetes, and chronic kidney diseases in diabetes. Increased GDF-15 level is linked with the progression and prognosis of the disease condition.
- Poids moléculaire
- 14.2 kDa
- NCBI Accession
- NP_004855
- Pathways
- SARS-CoV-2 Protein Interactome
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