P-Cadherin Protein (CDH3) (AA 18-654) (His tag)

N° du produit ABIN6964122

Cette protéine Recombinant P-Cadherin est produite dans HEK-293 Cells.

Aperçu rapide pour P-Cadherin Protein (CDH3) (AA 18-654) (His tag) (ABIN6964122)

Antigène: P-Cadherin (CDH3)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Détail du produit

Attributs du protein: AA 18-654

Purification/Conjugué: Cette P-Cadherin protéine est marqué à la His tag.

Fonction: Recombinant human CDH3 protein with C-terminal 6xHis tag

Specificité: CDH3 (Ser18-Gly654) 6xHis tag

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: P-Cadherin (CDH3)

Autre désignation: CDH3

Sujet: This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015]

Poids moléculaire: predicted molecular mass of 60.9 kDa after removal of the signal peptide. The apparent molecular mass of CDH3-His is 70-100 kDa due to glycosylation.

UniProt: P22223