P-Cadherin Protein (CDH3) (AA 108-654) (His tag)
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- Antigène Voir toutes P-Cadherin (CDH3) Protéines
- P-Cadherin (CDH3)
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 108-654
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Origine
- Cynomolgus
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette P-Cadherin protéine est marqué à la His tag.
- Fonction
- Cynomolgus CDH3/Cadherin 3 Protein
- Séquence
- Asp108-Gly654
- Attributs du produit
- Recombinant Cynomolgus CDH3/Cadherin 3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp108-Gly654.
- Pureté
- > 95 % as determined by Tris-Bis PAGE
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.37 μM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product CDH3 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in 20 mM PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- P-Cadherin (CDH3)
- Autre désignation
- CDH3 (CDH3 Produits)
- Synonymes
- CDH3 Protein, Cadherin-3 Protein, AI385538 Protein, Cadp Protein, Cdhp Protein, P-cadherin Protein, Pcad Protein, CDHP Protein, HJMD Protein, PCAD Protein, E-Cad Protein, E-cadherin Protein, EP-cadherin Protein, XTCAD-1 Protein, c-cadherin Protein, cadherin-1 Protein, cdh1 Protein, cdh1-b Protein, cdh3 Protein, cdhc-A Protein, cdhp Protein, hjmd Protein, l-cam Protein, lcam Protein, pcad Protein, uvo Protein, uvomorulin Protein, xb-cad Protein, xcdh1 Protein, CDH15 Protein, K-CAM Protein, cadherin 3 Protein, cadherin 3 L homeolog Protein, Cadherin-3 Protein, CDH3 Protein, Cdh3 Protein, cdh3.L Protein, cdh-3 Protein
- Sujet
- Placental-Cadherin (CDH3), a cell adhesion molecule, is associated with the function of cells to bind with other cells and the extracellular matrix (ECM). CDH3 is highly expressed in many malignancies, and has been proved it could be a serum marker to monitor colorectal cancer. Inhibited CDH3 expression could upregulate E-cadherin, downregulated N-cadherin, which may control invasion and migration.
- Poids moléculaire
- 61.11 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- XP_005592414
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