Topoisomerase II alpha Protein (AA 1354-1473)

N° du produit ABIN7013599

Cette protéine Recombinant Topoisomerase II alpha est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour Topoisomerase II alpha Protein (AA 1354-1473) (ABIN7013599)

Antigène: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: >90 % as determined by SDS-PAGE.

Détail du produit

Attributs du protein: AA 1354-1473

Séquence: AA 1354-1473

Attributs du produit: Cynomolgus TRAIL R2 / DR5 / TNFRSF10B Protein, His Tag (MALS verified)

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 50 mM Tris, 0.5 M KCl, pH 8.0

Stock: -80 °C

Détail du antigène

Antigène: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Autre désignation: TOP2A

Sujet: DNA topoisomerase 2-alpha (TOP2A) is also known as DNA topoisomerase II, alpha isozyme and TOP2. It is a topoisomerase which control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. Also it is the targets of anti-cancer drugs that cause treatment-related leukemias with balanced translocations.

Poids moléculaire: 12.8 kDa

NCBI Accession: NP_001058

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases