TACSTD2 Protein (AA 25-270) (Fc Tag)

N° du produit ABIN7092858

Protéine Recombinant TACSTD2 exprimée dans HEK-293 Cells.

Aperçu rapide pour TACSTD2 Protein (AA 25-270) (Fc Tag) (ABIN7092858)

Antigène: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Application: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Détail du produit

Attributs du protein: AA 25-270

Purification/Conjugué: Cette TACSTD2 protéine est marqué à la Fc Tag.

Fonction: Recombinant mouse Trop2 protein with C-terminal human Fc tag

Specificité: Mouse Trop2(Gln25-Gly270) hFc(Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Information d'application

Indications d'application: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Commentaires:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Autre désignation: Trop2

Sujet: Tpm-2,Trop-2
This gene belongs to the tropomyosin family which encodes proteins that bind to actin filaments and stabilize them by regulating access to actin modifying proteins. The encoded protein is a high molecular weight tropomyosin expressed in slow skeletal muscle. In humans, mutations in this gene are associated with nemaline myopathy, cap disease and distal arthrogryposis syndromes. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2013]

Poids moléculaire: predicted molecular mass of 54.1 kDa after removal of the signal peptide.The apparent molecular mass of mTrop2-hFc is 55-70 kDa due to glycosylation.

UniProt: Q8BGV3