TACSTD2 Protein (His tag)

N° du produit ABIN7319882

Cette protéine Recombinant TACSTD2 est produite dans Human Cells.

Aperçu rapide pour TACSTD2 Protein (His tag) (ABIN7319882)

Antigène: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Human Cells

Pureté: >95 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette TACSTD2 protéine est marqué à la His tag.

Fonction: Recombinant Human Tumor-associated Calcium Signal Transducer 2/TROP-2 (248AA, C-6His)

Séquence: His27-Thr274

Attributs du produit: Recombinant Human Tumor-associated Calcium Signal Transducer 2 is produced by our Mammalian expression system and the target gene encoding His27-Thr274 is expressed with a 6His tag at the C-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Immobilized Human TROP-2-His(Cat#C07M) at 2μg/ml (100 μl/well) can bind Anti-Human TROP-2 mAb. The ED50 of Anti-Human TROP-2 mAb is 13.03 ng/ml.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Autre désignation: Tumor-associated Calcium Signal Transducer 2/TROP-2

Sujet:

Background: Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87 % amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.

Synonym: Tumor-associated calcium signal transducer 2,Membrane component chromosome 1 surface marker 1,Cell surface glycoprotein Trop-2, TACSTD2,TROP2

Poids moléculaire: 28.9 kDa

UniProt: P09758