Interleukin 17a Protein (His tag)

N° du produit ABIN7121397

Cette protéine Recombinant Interleukin 17a est exprimée dans HEK-293 Cells.

Aperçu rapide pour Interleukin 17a Protein (His tag) (ABIN7121397)

Antigène: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Type de proteíne: Recombinant

Origine: Chien

Source: HEK-293 Cells

Pureté: >90 % as determined by SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette Interleukin 17a protéine est marqué à la His tag.

Fonction: Canine IL-17A / CTLA-8 Protein, His Tag

Séquence: Gly 26 - Ala 155

Attributs du produit: Canine IL-17A, His Tag (ILA-C52H7) is expressed from human 293 cells (HEK293). It contains AA Gly 26 - Ala 155 (Accession # C6L8D7-1).

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Indications d'application: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 17.0 kDa. The protein migrates as 18 kDa and 22 kDa under reducing (R) condition due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Autre désignation: IL-17A / CTLA-8

Sujet: Synonyms: IL-17A,Interleukin-17A,CTLA-8,IL-17,
Description: Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Poids moléculaire: 17.0 kDa

NCBI Accession: NM_001165878