Interleukin 17a Protein (AA 24-155) (His tag,AVI tag,Biotin)
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- Antigène Voir toutes Interleukin 17a (IL17A) Protéines
- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 24-155
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Interleukin 17a protéine est marqué à la His tag,AVI tag,Biotin.
- Séquence
- AA 24-155
- Specificité
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- Pureté
- >90 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL17A Protéine
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- Commentaires
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Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Conseil sur la manipulation
- Please avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
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- Antigène
- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
- Autre désignation
- IL-17A (IL17A Produits)
- Synonymes
- CTLA8 Protein, IL-17 Protein, IL-17A Protein, IL17 Protein, Ctla-8 Protein, Ctla8 Protein, Il17 Protein, ChIL-17 Protein, IL-17F Protein, IL17A Protein, CTLA-8 Protein, interleukin 17A Protein, IL17A Protein, Il17a Protein
- Sujet
- Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
- Poids moléculaire
- 17.8 kDa
- NCBI Accession
- NP_002181
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