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AKR1C2 Protéine

AKR1C2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
N° du produit ABIN7318143
  • Antigène Voir toutes AKR1C2 Protéines
    AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
    Type de proteíne
    Recombinant
    Origine
    Humain
    Source
    • 4
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Fonction
    Recombinant Human AKR1C2 Protein
    Séquence
    Met 1-Tyr323
    Attributs du produit
    Recombinant Human Aldo-Keto Reductase Family 1 Member C2 is produced by our E.coli expression system and the target gene encoding Met1-Tyr323 is expressed.
    Pureté
    > 90 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product AKR1C2 Protéine
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, pH 8.0.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
    Autre désignation
    AKR1C2 (AKR1C2 Produits)
    Synonymes
    AKR1C-pseudo Protein, BABP Protein, DD Protein, DD2 Protein, DDH2 Protein, HAKRD Protein, HBAB Protein, MCDR2 Protein, SRXY8 Protein, Akr1c21 Protein, aldo-keto reductase family 1 member C2 Protein, aldo-keto reductase family 1, member C2 Protein, AKR1C2 Protein, Akr1c2 Protein
    Sujet

    Background: Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).

    Synonym: Aldo-Keto Reductase Family 1 Member C2, 3-Alpha-HSD3, Chlordecone Reductase Homolog HAKRD, Dihydrodiol Dehydrogenase 2, DD-2, DD2, Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein, DD/BABP, Trans-1,2-Dihydrobenzene-1,2-Diol Dehydrogenase, Type III 3-Alpha-Hydroxysteroid Dehydrogenase, AKR1C2, DDH2

    Poids moléculaire
    36.7 kDa
    UniProt
    P52895
    Pathways
    Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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