AKR1C2 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2714502

Détail du produit

Antigène: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette AKR1C2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human AKR1C2 / DDH2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Autre désignation: Akr1c2,ddh2 (AKR1C2 Produits)

Synonymes: AKR1C-pseudo Protein, BABP Protein, DD Protein, DD2 Protein, DDH2 Protein, HAKRD Protein, HBAB Protein, MCDR2 Protein, SRXY8 Protein, Akr1c21 Protein, aldo-keto reductase family 1 member C2 Protein, aldo-keto reductase family 1, member C2 Protein, AKR1C2 Protein, Akr1c2 Protein

Sujet: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.

Poids moléculaire: 36.6 kDa

NCBI Accession: NP_995317

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process