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Amphiregulin Protein (AREG)

Cette protéine Recombinant Amphiregulin est exprimée dans Escherichia coli (E. coli).
N° du produit ABIN7318151

Aperçu rapide pour Amphiregulin Protein (AREG) (ABIN7318151)

Antigène

Voir toutes Amphiregulin (AREG) Protéines
Amphiregulin (AREG)

Type de proteíne

Recombinant

Origine

  • 9
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Humain

Source

  • 18
  • 3
  • 1
  • 1
Escherichia coli (E. coli)

Pureté

> 95 % as determined by reducing SDS-PAGE.
  • Fonction

    Recombinant Human Amphiregulin/AREG Protein

    Séquence

    Ser101-Lys198

    Attributs du produit

    Recombinant Human Amphiregulin is produced by our E.coli expression system and the target gene encoding Ser101-Lys198 is expressed.

    niveau d'endotoxine

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

    Stock

    4 °C,-20 °C,-80 °C

    Stockage commentaire

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène

    Amphiregulin (AREG)

    Autre désignation

    Amphiregulin/AREG

    Sujet

    Background: Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGF-alpha). As an EGF-related growth factor, AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. AREG may also play a protective role in Bleomycin-Induced Pneumopathy.

    Synonym: Amphiregulin, AR, Colorectum Cell-Derived Growth Factor, CRDGF, AREG, SDGF, AREGB

    Poids moléculaire

    11.4 kDa

    UniProt

    P15514

    Pathways

    Signalisation RTK, EGFR Signaling Pathway
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