Annexin V Protéine

N° du produit ABIN7317864

Cette protéine Recombinant Annexin V est produite dans Escherichia coli (E. coli).

Aperçu rapide pour Annexin V Protéine (ABIN7317864)

Antigène: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 90 % as determined by reducing SDS-PAGE.

Détail du produit

Fonction: Recombinant Human ANXA5/Annexin V/Annexin A5 Protein

Séquence: Met 1-Asp 320

Attributs du produit: A DNA sequence encoding the human ANXA5 (P08758) (Met 1-Asp 320) was expressed and purified.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 50 mM Tris, 240 mM NaCl, pH 8.5

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Autre désignation: ANXA5/Annexin V/Annexin A5

Sujet:

Background: Peptidyl-prolyl cis-trans isomerase A; also known as PPIase A; Rotamase A; Cyclophilin A; Cyclosporin A-binding protein; PPIA and CYPA; is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins (CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity; suggesting that they influence the conformation of proteins in cells. PPIA / Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA / Cyclophilin A is secreted by vascular smooth muscle cells in response to inflammatory stimuli; and could thus contribute to atherosclerosis. It is not essential for mammalian cell viability. PPIA / Cyclophilin A can interact with several HIV proteins; including p55 gag; Vpr; and capsid protein; and has been shown to be necessary for the formation of infectious HIV virions.

Synonym: ANXA5;Annexin V;Unconjugated Annexin V;Annexin-5;Anchorin CII;Calphobindin I;Endonexin II;Lipocortin V;Placental anticoagulant protein 4;Placental anticoagulant protein I;Thromboplastin inhibitor;Vascular anticoagulant-alpha

Poids moléculaire: 35.9 kDa

UniProt: P08758

Pathways: Apoptose