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CPE Protein (His tag)

CPE Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7318246
  • Antigène Voir toutes CPE Protéines
    CPE (Carboxypeptidase E (CPE))
    Type de proteíne
    Recombinant
    Origine
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette CPE protéine est marqué à la His tag.
    Fonction
    Recombinant Human Carboxypeptidase E/CPE Protein (His Tag)
    Séquence
    Arg42-Ser453
    Attributs du produit
    Recombinant Human Carboxypeptidase E is produced by our Mammalian expression system and the target gene encoding Arg42-Ser453 is expressed with a 6His tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CPE Protéine
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM ZnCl2,10 % Glycerol, pH 7.5.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    CPE (Carboxypeptidase E (CPE))
    Autre désignation
    Carboxypeptidase E/CPE (CPE Produits)
    Synonymes
    CPE Protein, CPH Protein, Cph-1 Protein, Cph1 Protein, R74677 Protein, fat Protein, CARBE Protein, Cph Protein, si:ch211-198g9.2 Protein, zgc:85981 Protein, carboxypeptidase E Protein, carboxypeptidase E L homeolog Protein, CPE Protein, cpe Protein, Cpe Protein, cpe.L Protein
    Sujet

    Background: The active form of CPE cleaves C-terminal amino acid residues of the peptide, and is thus involved in the biosynthesis of peptide hormones and neurotransmitters including insulin, enkephalin, etc. It is thought that membrane-associated CPE acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway. Defects in this protein are implicated in type II diabetes due to impaired glucose clearance and insulin resistance.

    Synonym: Carboxypeptidase E(CPE for short), Carboxypeptidase H, Enkephalin convertase, Prohormone-processing carboxypeptidase

    Poids moléculaire
    47.1 kDa
    UniProt
    P16870
    Pathways
    Peptide Hormone Metabolism, Synaptic Membrane
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