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Cardiotrophin 1 Protein (CTF1) (His tag)

CTF1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7318248
  • Antigène Voir toutes Cardiotrophin 1 (CTF1) Protéines
    Cardiotrophin 1 (CTF1)
    Type de proteíne
    Recombinant
    Origine
    • 8
    • 3
    • 3
    • 1
    Humain
    Source
    • 10
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette Cardiotrophin 1 protéine est marqué à la His tag.
    Fonction
    Recombinant Human Cardiotrophin-1/CTF1 Protein (His Tag)
    Séquence
    Met 1-Ala201
    Attributs du produit
    Recombinant Human Cardiotrophin-1 is produced by our E.coli expression system and the target gene encoding Met1-Ala201 is expressed with a 6His tag at the N-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CTF1 Protéine
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    Cardiotrophin 1 (CTF1)
    Autre désignation
    Cardiotrophin-1/CTF1 (CTF1 Produits)
    Synonymes
    CTF1 Protein, ct1 Protein, ct-1 Protein, ctf2 Protein, CT-1 Protein, CT1 Protein, cardiotrophin 1 Protein, cardiotrophin-1 Protein, CTF1 Protein, ctf1 Protein, Ctf1 Protein, LOC100736818 Protein
    Sujet

    Background: Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate and ovary, and to lower levels in lung, kidney, pancreas, thymus, testis and small intestine. The protein exerts its cellular effects by interacting with the glycoprotein 130 (gp130)/leukemia inhibitory factor receptor beta (LIFR) heterodimer. In addition, CT-1 activates phosphatidylinositol 3-kinase (PI-3 kinase) in cardiac myocytes and enhances transcription factor NF-κB DNA -binding activities.

    Synonym: Cardiotrophin-1, CT-1, CTF1,

    Poids moléculaire
    22.6 kDa
    UniProt
    Q16619
    Pathways
    Signalistation JAK/STAT
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