CRADD Protéine
Aperçu rapide pour CRADD Protéine (ABIN7319673)
Antigène
Voir toutes CRADD ProtéinesType de proteíne
Origine
Source
Pureté
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Fonction
- Recombinant Human CRADD/RAIDD Protein
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Séquence
- Met1-Glu199
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Attributs du produit
- Recombinant Human CRADD is produced by our E.coli expression system and the target gene encoding Met1-Glu199 is expressed.
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niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
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!Découvrez nos protéines personnalisées prédéfinies et nos services de protéines sur mesure !ProduitSystème d'expressionConjuguéOriginPrix à partir deSystème d'expression HEK-293 CellsConjugué His tagOrigin HumanPrix à partir de 12.620,45 €Système d'expression Cell-free protein synthesis (CFPS)Conjugué Strep TagOrigin HumanPrix à partir de 18.117,43 €Votre projet nécessite-t-il une personnalisation supplémentaire ? Contactez-nous et découvrez nos solutions protéiques sur mesure
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CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) protein (His tag)
custom-made CRADD Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) protein (His tag)custom-made CRADD Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) protein (His-IF2DI Tag)CRADD Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) protein (GST tag)CRADD Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199), (full length) protein (His-SUMO Tag)CRADD Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
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Autre désignation
- CRADD/RAIDD
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Sujet
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Background: Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2, and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numerous tissues. Defects in CRADD will result in mental retardation.
Synonym: Death Domain-Containing Protein CRADD, Caspase and RIP Adapter with Death Domain, RIP-Associated Protein with A Death Domain, CRADD, RAIDD
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Poids moléculaire
- 23 kDa
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UniProt
- P78560
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Pathways
- Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
Antigène
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