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CD82 Protein (CD82) (Fc Tag)

CD82 Origine: Humain Hôte: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7319825
  • Antigène Voir toutes CD82 Protéines
    CD82
    Type de proteíne
    Recombinant
    Origine
    • 4
    • 3
    Humain
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette CD82 protéine est marqué à la Fc Tag.
    Fonction
    Recombinant Human CD82 (N-Fc)
    Séquence
    Gly103-Gln225
    Attributs du produit
    Recombinant Human CD82 Antigen is produced by our Mammalian expression system and the target gene encoding Gly103-Gln225 is expressed with a Fc tag at the N-terminus.
    Pureté
    >95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD82 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    CD82
    Autre désignation
    CD82 (CD82 Produits)
    Synonymes
    AA682076 Protein, AL023070 Protein, C33 Protein, IA4 Protein, Kai1 Protein, Tspan27 Protein, 4F9 Protein, GR15 Protein, KAI1 Protein, R2 Protein, SAR2 Protein, ST6 Protein, TSPAN27 Protein, CD82 antigen Protein, CD82 molecule Protein, Cd82 molecule Protein, Cd82 Protein, CD82 Protein
    Sujet

    Background: CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.

    Synonym: CD82 antigenC33, CD82 Molecule, CD82, IA4, IA4C33 antigen, Inducible membrane protein R2, KAI1, KAI1GR15, ST6, ST6tspan-27, Suppressor of tumorigenicity 6 protein, Tetraspanin-27, TSPAN27, Tspan-27, TSPAN274F9

    Poids moléculaire
    40.3 kDa
    UniProt
    P27701
    Pathways
    Signalisation p53
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