M-CSF/CSF1 Protéine

N° du produit ABIN7321260

Cette protéine Recombinant M-CSF/CSF1 est produite dans Human Cells.

Aperçu rapide pour M-CSF/CSF1 Protéine (ABIN7321260)

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Type de proteíne: Recombinant

Origine: Rat

Source: Human Cells

Pureté: > 95 % as determined by SDS-PAGE

Détail du produit

Fonction: Recombinant Rat M-CSF/CSF1 Protein

Séquence: Gln33-Arg254

Attributs du produit: Recombinant Rat Macrophage colony-stimulating factor 1 is produced by our Mammalian expression system and the target gene encoding Gln33-Arg254 is expressed.

niveau d'endotoxine: <1.0 EU per μg as determined by LAL test.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Autre désignation: M-CSF/CSF1

Sujet:

Background: Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance.

Synonym: Macrophage colony-stimulating factor 1, CSF-1, M-CSF, MCSF, CSF1

Poids moléculaire: 25.2 kDa

UniProt: Q8JZQ0

Pathways: Signalisation RTK