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GNMT Protein (His tag)

GNMT Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7318543
  • Antigène Voir toutes GNMT Protéines
    GNMT (Glycine N-Methyltransferase (GNMT))
    Type de proteíne
    Recombinant
    Origine
    • 10
    • 1
    • 1
    • 1
    Humain
    Source
    • 6
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette GNMT protéine est marqué à la His tag.
    Fonction
    Recombinant Human GNMT Protein (His Tag)
    Séquence
    Met 1-Asg294
    Attributs du produit
    Recombinant Human Glycine N-Methyltransferase is produced by our E.coli expression system and the target gene encoding Met1-Asg294 is expressed with a 6His tag at the N-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product GNMT Protéine
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    GNMT (Glycine N-Methyltransferase (GNMT))
    Autre désignation
    GNMT (GNMT Produits)
    Synonymes
    glycine N-methyltransferase Protein, CpipJ_CPIJ015956 Protein, Gnmt Protein, GNMT Protein
    Sujet

    Background: Glycine N-Methyltransferase (GNMT) is a tetrameric cytosolic protein. GNMT catalyzes the synthesis of N-methylglycine from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. It can affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine, playing an important role in maintaining normal AdoMet levels. GNMT is highly expressed in liver. As a major folate-binding protein, GNMT takes part in the detoxification pathway. Defects in GNMT are the cause of hypermethioninemia. the patients with this deficiency are mild hepatomegaly and chronic elevation of serum transaminases.

    Synonym: Glycine N-Methyltransferase, GNMT

    Poids moléculaire
    34.9 kDa
    UniProt
    Q14749
    Pathways
    Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
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