IgG2a Fc (AA 98-322) Protéine

N° du produit ABIN7321258

Protéine Recombinant IgG2a Fc exprimée dans HEK-293 Cells.

Aperçu rapide pour IgG2a Fc (AA 98-322) Protéine (ABIN7321258)

Antigène: IgG2a Fc

Type de proteíne: Recombinant

Origine: Rat

Source: HEK-293 Cells

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Attributs du protein: AA 98-322

Fonction: Recombinant Rat IgG2A Fc/Igg-2a Protein

Séquence: Val98-Lys322

Attributs du produit: Recombinant Rat Immunoglobulin G2A Fc is produced by our Mammalian expression system and the target gene encoding Val98-Lys322 is expressed.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, pH 8.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: IgG2a Fc

Autre désignation: IgG2A Fc/Igg-2a

Sujet: Ig gamma-2A chain C region,Igg-2a,Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains-two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78 % amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and CH3, which cause the diffrence in the interaction with complement, NK and mast cells, induction or inhibition by specific cytokines, and ability to cross the placenta.

Poids moléculaire:

Calculated MW: 35.2 kDa

Observed MW: 30-35 kDa

UniProt: P20760