IgG2a Fc protein (Fc Tag)

N° du produit ABIN7321258

Protéine Recombinant exprimée dans Human Cells.

Aperçu rapide pour IgG2a Fc protein (Fc Tag) (ABIN7321258)

Antigène: IgG2a Fc

Type de proteíne: Recombinant

Origine: Rat

Source: Human Cells

Pureté: > 95 % as determined by SDS-PAGE

Détail du produit

Purification/Conjugué: Fc Tag

Fonction: Recombinant Rat IgG2A Fc/Igg-2a Protein

Séquence: Val98-Lys322

Attributs du produit: Recombinant Rat Immunoglobulin G2A Fc is produced by our Mammalian expression system and the target gene encoding Val98-Lys322 is expressed.

niveau d'endotoxine: <1.0 EU per μg as determined by LAL test.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, pH 8.5.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: IgG2a Fc

Autre désignation: IgG2A Fc/Igg-2a

Sujet:

Background: Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains-two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78 % amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and CH3, which cause the diffrence in the interaction with complement, NK and mast cells, induction or inhibition by specific cytokines, and ability to cross the placenta.

Synonym: Ig gamma-2A chain C region, Igg-2a

Poids moléculaire: 35.2 kDa

UniProt: P20760