IDE Protein (His tag)
Aperçu rapide pour IDE Protein (His tag) (ABIN7318623)
Antigène
Voir toutes IDE ProtéinesType de proteíne
Origine
Source
Pureté
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Purification/Conjugué
- Cette IDE protéine est marqué à la His tag.
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Fonction
- Recombinant Human IDE/Insulysin Protein (His Tag)
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Séquence
- Met42-Leu1019
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Attributs du produit
- Recombinant Human Insulin-Degrading Enzyme is produced by our Mammalian expression system and the target gene encoding Met42-Leu1019 is expressed with a 6His tag at the C-terminus.
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niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
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!Découvrez nos protéines personnalisées prédéfinies et nos services de protéines sur mesure !ProduitSystème d'expressionConjuguéOriginPrix à partir deSystème d'expression HEK-293 CellsConjugué His tagOrigin HumanPrix à partir de 12.620,45 €Système d'expression Cell-free protein synthesis (CFPS)Conjugué Strep TagOrigin HumanPrix à partir de 18.117,43 €Votre projet nécessite-t-il une personnalisation supplémentaire ? Contactez-nous et découvrez nos solutions protéiques sur mesure
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Insulin-Degrading Enzyme (IDE) (AA 1-1019) protein (His tag)
custom-made IDE Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Insulin-Degrading Enzyme (IDE) (AA 1-1019) protein (His tag)custom-made IDE Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Insulin-Degrading Enzyme (IDE) (AA 920-1019) protein (GST tag)IDE Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Insulin-Degrading Enzyme (IDE) (AA 1-1019) protein (GST tag)IDE Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Insulin-Degrading Enzyme (IDE) protein (Myc-DYKDDDDK Tag)IDE Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,0.05 % Brij35,10 %Glycerol, pH 7.5.
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Stock
- -20 °C
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Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- IDE (Insulin-Degrading Enzyme (IDE))
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Autre désignation
- IDE/Insulysin
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Sujet
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Background: Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling. IDE degrades amyloid formed by APP and IAPP. IDE may participate in the degradation and clearance of naturally secreted amyloid β-protein by neurons and microglia. IDE, which migrates at 110 kDa during gel electrophoresis under denaturing conditions, has since been shown to have additional substrates, including the signaling peptides glucagon, TGF α and β-endorphin.
Synonym: Insulin-Degrading Enzyme, Abeta-Degrading Protease, Insulin Protease, Insulinase, Insulysin, IDE
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Poids moléculaire
- 114.3 kDa
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UniProt
- P14735
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Pathways
- SARS-CoV-2 Protein Interactome
Antigène
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