IL-11 Protein (AA 23-199)

N° du produit ABIN7319568

Cette protéine Recombinant IL-11 est exprimée dans Yeast (Pichia pastoris).

Aperçu rapide pour IL-11 Protein (AA 23-199) (ABIN7319568)

Antigène: IL-11 (IL11) (Interleukin 11 (IL11))

Type de proteíne: Recombinant

Origine: Humain

Source: Yeast (Pichia pastoris)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Attributs du protein: AA 23-199

Fonction: Recombinant Human Interleukin-11/IL-11 Protein

Séquence: Gly23-Leu199

Attributs du produit: Recombinant Human Interleukin-11 is produced by our Yeast expression system and the target gene encoding Gly23-Leu199 is expressed.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 2 % Glycine, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: IL-11 (IL11) (Interleukin 11 (IL11))

Autre désignation: Interleukin-11/IL-11

Sujet: Interleukin,Adipogenesis Inhibitory Factor,AGIF,AGIF (Adipogenesis Inhibitory Factor),IL-11,Interleukin-11,Oprelvekin,IL11,Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. IL-11 is a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. It also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2, It activates a signaling cascade that promotes cell proliferation. The signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.

Poids moléculaire:

Calculated MW: 19.0 kDa

Observed MW: 19 kDa

ID gène: 3589

UniProt: P20809

Pathways: Signalistation JAK/STAT, Negative Regulation of Hormone Secretion