IL-13 Protein (mFc Tag)

N° du produit ABIN7319863

Protéine Recombinant IL-13 exprimée dans Human Cells.

Aperçu rapide pour IL-13 Protein (mFc Tag) (ABIN7319863)

Antigène: IL-13 (IL13) (Interleukin 13 (IL13))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Pureté: >95 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette IL-13 protéine est marqué à la mFc Tag.

Fonction: Recombinant Human Interleukin-13/IL-13 (C-mFc)

Séquence: Gly21--Asn132

Attributs du produit: Recombinant Human Interleukin-13 is produced by our Mammalian expression system and the target gene encoding Gly21-Asn132 is expressed with a mFc tag at the C-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: IL-13 (IL13) (Interleukin 13 (IL13))

Autre désignation: Interleukin-13/IL-13

Sujet:

Background: Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.

Synonym: Interleukin-13, IL-13

Poids moléculaire: 38.7 kDa

Pathways: Signalistation JAK/STAT, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport