SGSH Protein (His tag)

N° du produit ABIN7318838

Protéine Recombinant SGSH exprimée dans Human Cells.

Aperçu rapide pour SGSH Protein (His tag) (ABIN7318838)

Antigène: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette SGSH protéine est marqué à la His tag.

Fonction: Recombinant Human SGSH Protein (His Tag)

Séquence: Arg21-Leu502

Attributs du produit: Recombinant Human N-Sulphoglucosamine Sulphohydrolase is produced by our Mammalian expression system and the target gene encoding Arg21-Leu502 is expressed with a 6His tag at the C-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM GaCl2,10 % Glycerol, pH 7.5.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Autre désignation: SGSH

Sujet:

Background: N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-sulfo-D-glucosamine and H2O to D-glucosamine and sulfate. SGSH deficiency is result in mucopolysaccharidosis type 3A (MPS3A), a recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations.

Synonym: N-Sulphoglucosamine Sulphohydrolase, Sulfoglucosamine Sulfamidase, Sulphamidase, SGSH, HSS

Poids moléculaire: 55.7 kDa

UniProt: P51688

Pathways: Glycosaminoglycan Metabolic Process