NFASC Protein (His tag)
Aperçu rapide pour NFASC Protein (His tag) (ABIN7317169)
Antigène
Voir toutes NFASC ProtéinesType de proteíne
Origine
Source
Pureté
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Purification/Conjugué
- Cette NFASC protéine est marqué à la His tag.
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Fonction
- Recombinant Human NFASC/Neurofascin protein (His Tag)
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Séquence
- Met 1-Gln939
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Attributs du produit
- A DNA sequence encoding the human NFASC (O94856-12) (Met1-Gln939) was expressed with a C-terminal polyhistidine tag.
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niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
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Neurofascin (NFASC) protein (Fc Tag)
NFASC Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Neurofascin (NFASC) (AA 1239-1347) protein (His tag)NFASC Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
Neurofascin (NFASC) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)NFASC Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Neurofascin (NFASC) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)NFASC Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- NFASC (Neurofascin (NFASC))
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Autre désignation
- NFASC/Neurofascin
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Sujet
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Background: NFASC, also known as neurofascin, belongs to the immunoglobulin superfamily, L1/neurofascin/NgCAM family. It contains 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. NFASC functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. NFASC links the AIS extracellular matrix to the intracellular cytoskeleton.
Synonym: NF,NRCAML
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Poids moléculaire
- 104.4 kDa
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Pathways
- Cell-Cell Junction Organization
Antigène
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