PFKM Protein (His-GST)

N° du produit ABIN7197337

Cette protéine Recombinant PFKM est exprimée dans Baculovirus infected Insect Cells.

Aperçu rapide pour PFKM Protein (His-GST) (ABIN7197337)

Antigène: PFKM (phosphofructokinase, Muscle (PFKM))

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Pureté: > 90 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette PFKM protéine est marqué à la His-GST.

Fonction: Recombinant Human PFK1/PFKM Protein (His & GST Tag)

Séquence: Thr 2-Val 780

Attributs du produit: A DNA sequence encoding the human PFKM (P08237-1) (Thr2-Val780) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, pH 8.5, 10 % glycerol

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: PFKM (phosphofructokinase, Muscle (PFKM))

Autre désignation: PFK1/PFKM

Sujet: 6-phosphofructokinase,ATP-PFK,GSD7,PFK-1,PFK1,PFKA,PFKM,PFKX,PPP1R122,Phosphofructo-1-kinase isozyme A,Phosphofructokinase 1,Phosphohexokinase,muscle type,PFK1, also known as PFKM, is a regulatory glycolytic enzyme. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. It is a muscle-type isozyme. There are three phosphofructokinase isozymes in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Mutations in PFK1 gene have been related with glycogen storage disease type VII, also identified as Tarui disease.

Poids moléculaire:

Calculated MW: 112.9 kDa

Observed MW: 113 kDa

ID gène: 5213

UniProt: P08237

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, L'effet Warburg