PMM1 Protein (His tag)
Aperçu rapide pour PMM1 Protein (His tag) (ABIN7318899)
Antigène
Voir toutes PMM1 ProtéinesType de proteíne
Origine
Source
Pureté
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Purification/Conjugué
- Cette PMM1 protéine est marqué à la His tag.
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Fonction
- Recombinant Human PMM1 Protein (His Tag)
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Séquence
- Met 1-Ala262
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Attributs du produit
- Recombinant Human Phosphomannomutase 1 is produced by our E.coli expression system and the target gene encoding Met1-Ala262 is expressed with a 6His tag at the C-terminus.
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niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 1 mM DTT, pH 8.0.
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Stock
- -20 °C
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Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- PMM1 (Phosphomannomutase 1 (PMM1))
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Autre désignation
- PMM1
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Sujet
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Background: Phosphomannomutase 1 (PMM1) blongs to the eukaryotic PMM family. Phosphomannomutase 1 can catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose which required for a number of critical mannosyl transfer reactions. PMM1 is highly expressed in liver, heart, brain, and pancreas, but lower expression in skeletal muscle. In addition, PMM1 may be responsible for the degradation of glucose-1,6 bisphosphate in ischemic brain.
Synonym: Phosphomannomutase 1, PMM 1, PMMH-22, PMM1, PMMH22
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Poids moléculaire
- 30.8 kDa
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UniProt
- Q92871
Antigène
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