Pleiotrophin Protein (PTN) (His tag)
Aperçu rapide pour Pleiotrophin Protein (PTN) (His tag) (ABIN7320789)
Antigène
Voir toutes Pleiotrophin (PTN) ProtéinesType de proteíne
Origine
Source
Pureté
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Purification/Conjugué
- Cette Pleiotrophin protéine est marqué à la His tag.
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Fonction
- Recombinant Mouse Pleiotrophin/PTN/HB-GAM Protein (His Tag)
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Séquence
- Gly33-Asp168
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Attributs du produit
- Recombinant Mouse Pleiotrophin is produced by our Mammalian expression system and the target gene encoding Gly33-Asp168 is expressed with a 6His tag at the C-terminus.
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niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
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Pleiotrophin (PTN) (AA 33-168) protein (Fc Tag)
PTN Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Pleiotrophin (PTN) protein (Fc Tag)PTN Origine: Souris Hôte: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
Pleiotrophin (PTN) (AA 1-168) protein (GST tag)PTN Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Pleiotrophin (PTN) (Active) proteinPTN Origine: Souris Hôte: Baculovirus infected Insect Cells Recombinant > 95 % as determined by SDS-PAGE Active
Pleiotrophin (PTN) (AA 33-168) protein (Fc Tag)PTN Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Pleiotrophin (PTN)
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Autre désignation
- Pleiotrophin/PTN/HB-GAM
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Sujet
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Background: Pleiotrophin (PTN) is an secreted, strongly heparinbinding,developmentally regulated cytokine. PTN and midkine share50 % amino acid (aa) sequence identity, share some functions, and constitute a family. PTN is a highly conserved protein? human, mouse, rat, canine, porcine, equine and bovine PTN share 98 % aa sequence identity orgreater. During development, PTN is involved in development of brain, bone, and organs undergoing branching morphogenesis. PTN causes PTPRB dimerization and inactivates its phosphatase activity, which allows increased tyrosine phosphorylation of its substrates. Increased expression of PTN is correlated withneuronal development or stresses such as brain ischemia and Parkinson's disease.
Synonym: Pleiotrophin, PTN, Heparin-binding brain mitogen, HBBM, Heparin-binding growth factor 8, HBGF-8, Osteoblast-specific factor 1, OSF-1,HARP,HB-GAM,HBBN,HBNF,OSF,Osf-1,Osf1
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Poids moléculaire
- 16.1 kDa
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UniProt
- P63089
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Pathways
- Signalisation RTK
Antigène
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