Vinculin Protein (VCL) (His tag)

N° du produit ABIN7198696

Cette protéine Recombinant Vinculin est exprimée dans HEK-293 Cells.

Aperçu rapide pour Vinculin Protein (VCL) (His tag) (ABIN7198696)

Antigène: Vinculin (VCL)

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Pureté: > 90 % as determined by SDS-PAGE

Détail du produit

Purification/Conjugué: Cette Vinculin protéine est marqué à la His tag.

Fonction: Recombinant Mouse VCL/Vinculin Protein (His Tag)

Séquence: Met1-Gln1066

Attributs du produit: A DNA sequence encoding the mouse VCL (NP_033528.3) (Met1-Gln1066) was expressed with a C-terminal polyhistidine tag.

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Vinculin (VCL)

Autre désignation: VCL/Vinculin

Sujet:

Background: Vinculin (VCL) is a cytoskeletal protein that is closely related to both cell-matrix interactions and cell-cell junctions. VCL is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. The protein contains an acidic N-terminal domain and a basic C-terminal domain separated by a proline-rich middle segment. This protein has multi-ligand properties and has been found to interact with a number of microfilament associated proteins, such as talin, a-actinin, and paxillin, which reportedly bind to either the head or tail domains of vinculin.

Synonym: 9430097D22,AA571387,AI462105,AW545629

Poids moléculaire: 118.2 kDa

NCBI Accession: NP_033528

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2