APOA5 Protein (AA 21-368) (His tag)

N° du produit ABIN7273849

Détail du produit

Antigène: APOA5 (Apolipoprotein A-V (APOA5))

Type de proteíne: Recombinant

Attributs du protein: AA 21-368

Origine: Souris

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette APOA5 protéine est marqué à la His tag.

Fonction: Mouse APOA5 Protein

Séquence: Arg21-Gly368

Attributs du produit: Recombinant Mouse APOA5 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Arg21-Gly368.

Pureté: > 95 % as determined by Tris-Bis PAGE

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl, 10 % Glycerol, 2 mM DTT ( pH 8.5).

Agent conservateur: Dithiothreitol (DTT)

Précaution d'utilisation: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -80 °C

Stockage commentaire: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: APOA5 (Apolipoprotein A-V (APOA5))

Autre désignation: APOA5 (APOA5 Produits)

Synonymes: APOAV Protein, RAP3 Protein, 1300007O05Rik Protein, Apoav Protein, apo-AV Protein, apoA-V Protein, APOA5 Protein, MGC140487 Protein, rap3 Protein, apoav Protein, apoa-v Protein, apolipoprotein A5 Protein, apolipoprotein A-V Protein, apolipoprotein A5 L homeolog Protein, APOA5 Protein, Apoa5 Protein, apoa5.L Protein, apoa5 Protein

Sujet: APOA5 is probably the gene with the strongest effect on triglyceride (TG) metabolism. APOA5 is almost exclusively expressed in the liver, and its product apoAV has a very low circulating concentration. New physiological roles of apoAV have been recently elucidated, such as control of chylomicron production in the intestine and TG accumulation in adipose tissue.The key role of APOA5 in TG metabolism has been largely shown through genetic studies in association with either severe or moderate hypertriglyceridemia.

Poids moléculaire: 40.5 kDa same as Tris-Bis PAGE result.

UniProt: Q8C7G5

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism