ApoE3 Protein (AA 19-317) (His tag)

N° du produit ABIN7273865

Protéine Recombinant ApoE3 exprimée dans HEK-293 Cells.

Aperçu rapide pour ApoE3 Protein (AA 19-317) (His tag) (ABIN7273865)

Antigène: ApoE3 (Apolipoprotein E3 (ApoE3))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: HEK-293 Cells

Pureté: > 95 % as determined by Bis-Tris PAGE,> 85 % as determined by HPLC

Détail du produit

Attributs du protein: AA 19-317

Purification/Conjugué: Cette ApoE3 protéine est marqué à la His tag.

Fonction: Human APOE3/Apolipoprotein E Protein

Séquence: Lys19-His317

Attributs du produit: Recombinant Human APOE3/Apolipoprotein E Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Lys19-His317.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Human APOE3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Human APOE3 is greater than 85% as determined by SEC-HPLC.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: ApoE3 (Apolipoprotein E3 (ApoE3))

Autre désignation: APOE3

Sujet: Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD).

Poids moléculaire: 35.3 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Bis-Tris PAGE result.

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism