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IgE Protein (AA 91-421) (His tag)

Cette protéine Recombinant IgE est produite dans HEK-293 Cells.
N° du produit ABIN7274856

Aperçu rapide pour IgE Protein (AA 91-421) (His tag) (ABIN7274856)

Antigène

Voir toutes IgE Protéines
IgE

Type de proteíne

Recombinant

Origine

  • 9
  • 7
  • 5
  • 4
  • 2
  • 1
Souris

Source

  • 11
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Pureté

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • Attributs du protein

    AA 91-421

    Purification/Conjugué

    Cette IgE protéine est marqué à la His tag.

    Fonction

    Mouse IgE Protein

    Séquence

    Val91-Ser421

    Attributs du produit

    Recombinant Mouse IgE Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val91-Ser421.

    Stérilité

    0.22 μm filtered

    niveau d'endotoxine

    Less than 1EU per ug by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    Buffer

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Date de péremption

    12 months
  • Antigène

    IgE

    Sujet

    Immunoglobulin E (IgE) is well known for its role in allergic disease, the manifestations of which are mediated through its two Fc receptors, FcεRI and CD23 (FcεRII). IgE and its interactions with these receptors are therefore potential targets for therapeutic intervention, and exciting progress has been made in this direction. Furthermore, recent structural studies of IgE-Fc, the two receptors, and of their complexes, have revealed a remarkable degree of plasticity at the IgE-CD23 interface and an even more remarkable degree of dynamic flexibility within the IgE molecule.

    Poids moléculaire

    38.5 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.

    UniProt

    P06336
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