MME Protein (AA 52-750) (His tag)

N° du produit ABIN7275263

Protéine Recombinant MME exprimée dans HEK-293 Cells.

Aperçu rapide pour MME Protein (AA 52-750) (His tag) (ABIN7275263)

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Détail du produit

Attributs du protein: AA 52-750

Purification/Conjugué: Cette MME protéine est marqué à la His tag.

Fonction: Human CD10/MME Protein

Séquence: Tyr52-Trp750

Attributs du produit: Recombinant Human CD10/MME Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Tyr52-Trp750.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in 50 mM MES, 100 mM NaCl, 1 mM ZnCl2, 10 % Glycerol ( pH 6.5). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Autre désignation: CD10

Sujet: CD10 is an endopeptidase that degrades various bioactive peptides in the extracellular matrix. In addition to enzymatic degradation, it affects multiple intracellular signal transduction pathways. CD10 expression has been extensively studied in human epithelial cancers of numerous organs and sites. CD10 expression pattern depended on the histotypes of thyroid lesions. When possible metastatic tumours and non-epithelial tumours are excluded, high CD10 expression may be useful in determining whether a primary thyroid carcinoma includes an anaplastic component.

Poids moléculaire: 80.9 kDa. Due to glycosylation, the protein migrates to 81-110 kDa based on Tris-Bis PAGE result.

UniProt: P08473

Pathways: Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration