CD28 Protein (CD28) (His tag)

N° du produit ABIN7447918

Cette protéine Recombinant CD28 est produite dans HEK-293 Cells.

Aperçu rapide pour CD28 Protein (CD28) (His tag) (ABIN7447918)

Antigène: CD28

Type de proteíne: Recombinant

Origine: Rat

Source: HEK-293 Cells

Pureté: 90,00 %

Détail du produit

Purification/Conjugué: Cette CD28 protéine est marqué à la His tag.

Fonction: Rat CD28 Protein, His Tag (BLI verified)

Séquence: Asn 20 - Leu 150

Attributs du produit: Rat CD28, His Tag is expressed from human 293 cells (HEK293). It contains AA Asn 20 - Leu 150 (Accession # P31042-1).

niveau d'endotoxine: 1.0 EU per μg

Information d'application

Commentaires:

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 16.9 kDa. The protein migrates as 30-37 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: CD28

Autre désignation: CD28

Sujet: Synonyms:CD28,Tp44,Description:T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.

Poids moléculaire: 16.9 kDa

NCBI Accession: NP_037253

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response