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CD34 Protein (CD34) (Biotin,His-Avi Tag)

Cette protéine Recombinant CD34 est exprimée dans HEK-293 Cells.
N° du produit ABIN7489026

Aperçu rapide pour CD34 Protein (CD34) (Biotin,His-Avi Tag) (ABIN7489026)

Antigène

Voir toutes CD34 Protéines
CD34

Type de proteíne

Recombinant

Origine

  • 16
  • 7
  • 1
  • 1
Humain

Source

  • 8
  • 8
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

Pureté

90 %

Classe de qualité

MALS verified
  • Purification/Conjugué

    Cette CD34 protéine est marqué à la Biotin,His-Avi Tag.

    Fonction

    Biotinylated Human CD34 Protein, His,Avitag™ (MALS verified)

    Séquence

    Ser 32 - Thr 290

    Attributs du produit

    Biotinylated Human CD34 Protein, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Ser 32 - Thr 290 (Accession # P28906-1).

    niveau d'endotoxine

    1.0 EU per μg
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  • Commentaires

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). (Biotin,10xHis , Avi) The protein has a calculated MW of 31.1 kDa. The protein migrates as 50-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Stock

    -20 °C

    Stockage commentaire

    -20°C
  • Antigène

    CD34

    Autre désignation

    CD34

    Sujet

    CD34 Molecule is a cluster of differentiation molecule present on certain cells within the human body. It is a cell surface glycoprotein and functions as a cell-cell adhesion factor. It may also mediate the attachment of stem cells to bone marrow extracellular matrix or directly to stromal cells. As a ~ 110 kDa monomeric cell surface antigen, CD34 is highly glycosylated with nine potential N-linked and numerous potential O-linked glycosylation sites in its extracellular domain. The CD34 protein is a member of a family of single-pass transmembrane sialomucin proteins that show expression on early hematopoietic and vascular-associated tissue. CD34 is also an important adhesion molecule and is required for T cells to enter lymph nodes. It is expressed on lymph node endothelia whereas the L-selectin to which it binds is on the T cell. It was indicated that CD34 is a phosphorylation target for activated PKC, and couples to the hematopoietic adapter protein CrkL, which were involved in CD34 signaling pathways. CD34 is abberantly expressed in many kinds of tumors and is implicated in leukemogenesis.

    Poids moléculaire

    31.1 kDa
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