IL-31 Protéine

N° du produit ABIN7488784

Protéine Recombinant IL-31 exprimée dans HEK-293 Cells.

Aperçu rapide pour IL-31 Protéine (ABIN7488784)

Antigène: IL-31 (IL31) (Interleukin 31 (IL31))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: 90 %

Classe de qualité: Premium grade

Détail du produit

Fonction: Human IL-31 Protein, premium grade

Séquence: Ser 24 - Thr 164

Attributs du produit: Human IL-31 Protein, premium grade is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Thr 164 (Accession # Q6EBC2-1).

niveau d'endotoxine: 0.1 EU per μg

Information d'application

Commentaires:

This protein carries no "tag". () The protein has a calculated MW of 15.8 kDa. The protein migrates as 18-20 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: IL-31 (IL31) (Interleukin 31 (IL31))

Autre désignation: IL-31

Sujet: IL-31 is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. May function in skin immunity. IL-31 is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor β (OSMRβ) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways.

Poids moléculaire: 15.8 kDa