SEZ6 Protein (AA 20-925) (His-Avi Tag,Biotin)

N° du produit ABIN7504525

Cette protéine Recombinant SEZ6 est exprimée dans HEK-293 Cells.

Aperçu rapide pour SEZ6 Protein (AA 20-925) (His-Avi Tag,Biotin) (ABIN7504525)

Antigène: SEZ6 (Seizure Related 6 Homolog (SEZ6))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Détail du produit

Attributs du protein: AA 20-925

Purification/Conjugué: Cette SEZ6 protéine est marqué à la His-Avi Tag,Biotin.

Fonction: Biotinylated Human SEZ6 Protein

Séquence: Leu20-His925

Attributs du produit: Recombinant Biotinylated Human SEZ6 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Leu20-His925.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: SEZ6 (Seizure Related 6 Homolog (SEZ6))

Autre désignation: SEZ6

Sujet: Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface.

Poids moléculaire: 100.7 kDa. Due to glycosylation, the protein migrates to 170-200 kDa based on Tris-Bis PAGE result.

UniProt: Q53EL9-1

Pathways: Synaptic Membrane