Angiopoietin 1 Protein (ANGPT1) (His tag)
Aperçu rapide pour Angiopoietin 1 Protein (ANGPT1) (His tag) (ABIN7536327)
Antigène
Voir toutes Angiopoietin 1 (ANGPT1) ProtéinesType de proteíne
Origine
Source
Pureté
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Purification/Conjugué
- Cette Angiopoietin 1 protéine est marqué à la His tag.
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Fonction
- Recombinant Mouse Angiopoietin-1/ANG-1/ANGPT1 Protein
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Séquence
- REEEKPFRDC ADVYQAGFNK SGIYTIYFNN MPEPKKVFCN MDVNGGGWTV IQHREDGSLD FQRGWKEYKM GFGNPSGEYW LGNEFIFAIT SQRQYMLRIE LMDWEGNRAY SQYDRFHIGN EKQNYRLYLK GHTGTAGKQS SLILHGADFS TKDADNDNCM CKCALMLTGG WWFDACGPSN LNGMFYTAGQ NHGKLNGIKW HYFKGPSYSL RSTTMMIRPL DF
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Specificité
- Arg277-Phe498
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Stérilité
- 0.22 μm filtered
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niveau d'endotoxine
- <0.001EU/μg
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
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Concentration
- 0.92 mg/mL
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Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Angiopoietin 1 (ANGPT1)
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Autre désignation
- Angiopoietin-1/ANG-1/ANGPT1
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Sujet
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Description: The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In disease, ANGPT2-mediated inhibition of TIE2 in blood vessels is linked to vascular leak, inflammation, and metastasis.
Name: Ang1, Ang-1, 1110046O21Rik
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ID gène
- 11600
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UniProt
- O08538
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Pathways
- Signalisation RTK, Glycosaminoglycan Metabolic Process
Antigène
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