Angiopoietin 1 Protein (ANGPT1) (His tag)

N° du produit ABIN7536327

Détail du produit

Antigène: Angiopoietin 1 (ANGPT1)

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette Angiopoietin 1 protéine est marqué à la His tag.

Fonction: Recombinant Mouse Angiopoietin-1/ANG-1/ANGPT1 Protein

Séquence: REEEKPFRDC ADVYQAGFNK SGIYTIYFNN MPEPKKVFCN MDVNGGGWTV IQHREDGSLD FQRGWKEYKM GFGNPSGEYW LGNEFIFAIT SQRQYMLRIE LMDWEGNRAY SQYDRFHIGN EKQNYRLYLK GHTGTAGKQS SLILHGADFS TKDADNDNCM CKCALMLTGG WWFDACGPSN LNGMFYTAGQ NHGKLNGIKW HYFKGPSYSL RSTTMMIRPL DF

Specificité: Arg277-Phe498

Pureté: > 97 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: <0.001EU/μg

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Concentration: 0.92 mg/mL

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Détail du antigène

Antigène: Angiopoietin 1 (ANGPT1)

Autre désignation: Angiopoietin-1/ANG-1/ANGPT1 (ANGPT1 Produits)

Synonymes: AGP1 Protein, AGPT Protein, ANG1 Protein, 1110046O21Rik Protein, Ang-1 Protein, Ang1 Protein, Agpt Protein, Agpt1 Protein, ang1 Protein, wu:fc76g06 Protein, ANG-1 Protein, angpt1 Protein, MGC80788 Protein, angiopoietin 1 Protein, angiopoietin 1 S homeolog Protein, ANGPT1 Protein, Angpt1 Protein, angpt1 Protein, angpt1.S Protein

Sujet:

Description: The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In disease, ANGPT2-mediated inhibition of TIE2 in blood vessels is linked to vascular leak, inflammation, and metastasis.

Name: Ang1, Ang-1, 1110046O21Rik

ID gène: 11600

UniProt: O08538

Pathways: Signalisation RTK, Glycosaminoglycan Metabolic Process