CD47 Protein (CD47) (Fc Tag)

N° du produit ABIN7536134

Cette protéine Recombinant CD47 est produite dans HEK-293 Cells.

Aperçu rapide pour CD47 Protein (CD47) (Fc Tag) (ABIN7536134)

Antigène: CD47

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Rat

Source: HEK-293 Cells

Pureté: > 97 % by SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette CD47 protéine est marqué à la Fc Tag.

Fonction: Active Recombinant Rat CD47 Protein

Séquence: QLLLSKVKSV EFTSCNDTVV IPCKVLNVEA QSTDEMFVKW KLNKSYIFIY DGNKNSTTRE QNFTSAKISV SDLLKGIASL TMDTHEAVVG NYTCEVTELS REGKTVIELK NRPVSWFSTN EK

Specificité: Gln 19 - Lys 140

Stérilité: 0.22 μm filtered

niveau d'endotoxine: <0.1EU/μg

Biological Activity Comment: Measured by its binding ability in a functional ELISA.Immobilized Human CD172a at 2 μg/mL (100 μL/well) can bind Human CD47 with a linear range of 19.5-3491.5ng/mL.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Détail du antigène

Antigène: CD47

Autre désignation: CD47

Sujet:

Description: CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.

Name: Itgp,CD47

ID gène: 29364

UniProt: P97829